Valentine White of Isle of Wight County purchased 195 acres in Brunswick County from Nathaniel Barlow on 14 February 1740/1 [Brunswick Co., Va., Deed Bk. 3, p. 271]

It is possible that the connection with the Barlow family goes back to Norfolk County.

The Barlow family of Isle of Wight was descended from Henry Barlow of Lower Norfolk County.  Perhaps it is coincidental, but Henry Barlow's son Thomas started appearing in Isle Of Wight County records in 1663, which is about the same time John White married Eady Llewellin of Isle of Wight County
(Lundie W. Barlow, "Barlow of Isle of Wight, Virginia," in John Bennett Boddie, "Historical Southern Families," v. 2 [Redwood City, Calif., 1958], p. 22)

Nathaniel Barlow was the son of John Barlow who left a will in Surry County, dated 07 July 1727 (Eliza Timberlake Davis, "Wills and Administrations of Surry County, Virginia, 1671-1750" [reprint, Baltimore, 1980], p. 11)

Barlow does not show John Barlow as a descendant of Henry Barlow.  However, the Isle of Wight Barlow family did use the name Nathaniel.  John Barlow mentioned in his will a John White who might have been the son of Thomas and Ann (Moore) White, and possibly the same John White who died in Isle of Wight ca. 1754 and whose estate was appraised by John Barlow. Jr.
(Blanch Adams Chapman, "Wills and Administrations of Isle of Wight Co., Virginia, 1647-1800" [reprint, Baltimore, 1975], p. 177)

The Moore family was closely connected to the Barlow family in Isle of Wight County.  Probably, John Barlow who died in Surry County in 1727 was related somehow to the Isle of Wight Barlows, but the relationship is not known.

On 06 November 1651 the Lower Norfolk County court ordered Thomas Sayer to pay Henry Barlowe 2000 pounds of tobacco (Walter, op. cit., p. b-185)

On 09 March 1652/3 Henry Barlow was granted 350 acres on Julians Creek in Lower Norfolk County (Nugent, op. cit., v. 1. p. 274) These records show that Henry Barlow probably knew Thomas White.